Indirect modulation of the intracellular c-Di-GMP level in Shewanella oneidensis MR-1 by MxdA |
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| Authors: | Rakshe Shauna Leff Maija Spormann Alfred M |
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| Affiliation: | Departments of Chemical Engineering,1 Biological Science,2 Civil and Environmental Engineering, Stanford University, Stanford, California 94305-54293 |
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| Abstract: | The GGDEF domain protein MxdA, which is important for biofilm formation in Shewanella oneidensis MR-1, was hypothesized to possess diguanylate cyclase activity. Here, we demonstrate that while MxdA controls the cellular level of c-di-GMP in S. oneidensis, it modulates the c-di-GMP pool indirectly. |
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