| DCCP and DICP： Construction and Analyses of Databases for Copper- and Iron-Chelating Proteins |
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| 作者姓名： | Wu H Yang Y Jiang SJ Chen LL Gao HX Fu QS Li F Ma BG Zhang HY |
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| 作者单位： | [1]Shandong Provincial Research Center for Bioinformatic Engineering and Technique, Shandong University ofTechnology, Zibo 255049, China [2]Isotope Research Laboratory, Sichuan Agriculture University, Yaan 625014,China [3]College of Life Sciences, Shandong Normal University, Jinan 250014, China. |
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| 基金项目： | We are grateful to Chuan-Wei Dong, Wen-Bin Ding, Wei Sun, and Wei Wang for their help in constructing the databases. This work was supported by the National Basic Research Program of China （2003CB114400） and the National Natural Science Foundation of China （Grant No. 30100035）. |
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| 摘 要： | Copper and iron play important roles in a variety of biological processes, especially when being chelated with proteins. The proteins involved in the metal binding, transporting and metabolism have aroused much interest. To facilitate the study on this topic, we constructed two databases （DCCP and DICP） containing the known copper- and iron-chelating proteins~ which are freely available from the website http：//sdbi.sdut.edu.cn/en. Users can conveniently search and browse all of the entries in the databases. Based on the two databases, bioinformatic analyses were performed, which provided some novel insights into metalloproteins.
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| 关 键 词： | 生物学 铜元素 铁元素 钳合蛋白 金属粘合物 数据库 DCCP DICP |
DCCP and DICP: construction and analyses of databases for copper- and iron-chelating proteins |
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| Wu H,Yang Y,Jiang SJ,Chen LL,Gao HX,Fu QS,Li F,Ma BG,Zhang HY.DCCP and DICP: construction and analyses of databases for copper- and iron-chelating proteins[J].Genomics Proteomics & Bioinformatics,2005,3(1):52-57. |
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| Authors: | Wu Hao Yang Yan Jiang Sheng Juan Chen Ling Ling Gao Hai Xia Fu Qing Shan Li Feng Ma Bin Guang Zhang Hong Yu |
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| Institution: | Shandong Provincial Research Center for Bioinformatic Engineering and Technique, Shandong University of Technology, Zibo 255049, China. |
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| Abstract: | Copper and iron play important roles in a variety of biological processes, especially when being chelated with proteins. The proteins involved in the metal binding, transporting and metabolism have aroused much interest. To facilitate the study on this topic, we constructed two databases (DCCP and DICP) containing the known copper- and iron-chelating proteins, which are freely available from the website http://sdbi.sdut.edu.cn/en. Users can conveniently search and browse all of the entries in the databases. Based on the two databases, bioinformatic analyses were performed, which provided some novel insights into metalloproteins. |
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| Keywords: | copper and iron database primary sequence analysis secondary structure prediction SCOP classification |
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