Increase in NK-activity using superlow doses of the immunomodulator cycloferon |
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| Authors: | Shevchenko E V Finkel'shte?n B B Ivanov V A |
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| Institution: | Institute of Cytology RAS, St. Petersburg. shev@svs.ru |
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| Abstract: | A possibility of rising the antitumor activity of natural killers using various doses of the immunomodulator cycloferon was evaluated. A direct correlation has been revealed between the killer activity and the cycloferon dose. However, on a decrease in cycloferon concentrations by several orders, as compared with commonly accepted doses, this correlation changed for inverse. A possible mechanism of this effect is discussed in addition to practical significance of the obtained results. |
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