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Genotyping of Mycobacterium tuberculosis clinical isolates in two cities of Turkey: Description of a new family of genotypes that is phylogeographically specific for Asia Minor
Authors:Thierry?Zozio,Caroline?Allix,Selami?Gunal,Zeynep?Saribas,Alpaslan?Alp,Riza?Durmaz,Maryse?Fauville-Dufaux,Nalin?Rastogi  author-information"  >  author-information__contact u-icon-before"  >  mailto:nrastogi@pasteur-guadeloupe.fr"   title="  nrastogi@pasteur-guadeloupe.fr"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author,Christophe?Sola  author-information"  >  author-information__contact u-icon-before"  >  mailto:csola@pasteur-guadeloupe.fr"   title="  csola@pasteur-guadeloupe.fr"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author
Affiliation:1.Unité de la Tuberculose et des Mycobactéries,Institut Pasteur de,Guadeloupe;2.Laboratoire de la Tuberculose,Institut Pasteur de,Bruxelles;3.Department of Clinical Microbiology, Faculty of Medicine,Inonu Universit,Malatya,Turkey;4.Department of Microbiology and Clinical Microbiology, Faculty of Medicine,Hacettepe University,Ankara,Turkey
Abstract:

Background  

Population-based bacterial genetics using repeated DNA loci is an efficient approach to study the biodiversity and phylogeographical structure of human pathogens, such as Mycobacterium tuberculosis, the agent of tuberculosis. Indeed large genetic diversity databases are available for this pathogen and are regularly updated. No population-based polymorphism data were yet available for M. tuberculosis in Turkey, at the crossroads of Eurasia.
Keywords:
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