Characterization of <Emphasis Type="Italic">TRZ1</Emphasis>, a yeast homolog of the human candidate prostate cancer susceptibility gene ELAC2 encoding tRNase Z期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Characterization of <Emphasis Type="Italic">TRZ1</Emphasis>, a yeast homolog of the human candidate prostate cancer susceptibility gene ELAC2 encoding tRNase Z

Authors:	Email author" target="_blank">Yang?Chen Email author Audrey?Beck Christina?Davenport Yuan?Chen Donna?Shattuck Sean?V?Tavtigian

Institution:	(1) Myriad Genetics, Inc., 320 Wakara Way, Salt Lake City, UT 84108, USA;(2) International Agency for Research on Cancer, World Health Organization, 150 Cours Albert-Thomas, 69372 Lyon Cedex 08, France

Abstract:	Background In humans, mutation of ELAC2 is associated with an increased risk of prostate cancer. ELAC2 has been shown to have tRNase Z activity and is associated with the γ-tubulin complex.

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