30例妊娠妇女阴道微生态改变

目的 探讨妊娠妇女的阴道微生态变化.方法 采用检测妊娠妇女雌、孕激素水平、阴道理化指标及部分阴道常见菌群来分析阴道微生态的改变.结果 (1)孕妇组阴道白细胞数较高,与育龄健康组妇女相比,差异有统计学意义(P＜0.01)；唾液酸酶在两组间相比,差异无统计学意义(P＞0.05)；育龄妇女组阴道内的乳酸杆菌含量最高,与孕妇组相比,差异有统计学意义(P＜0.01)；大肠埃希菌含量在育龄妇女组最少,与孕妇组相比,差异有统计学意义(P＜0.05)；两组加德纳菌相比,差异无统计学意义(P＞0.05).结论 育龄妇女与妊娠妇女的阴道微生态环境不同,与其体内的雌、孕激素水平有关.

Changes of vaginal microecology in 30 pregnent women

Objective To discuss the vaginal microecological changes of pregnancy women. Methods The levels of estrogen and progestogen, physical and chemical indices as well as certain bacterial flora were measured to investigate the changes of vaginal microecology. Results The level of leukocyte in the pregnancy women was obviously higher than that of childbearing women. The difference between these two groups was statistically significant （ P 〈 0.01 ）. There was no significant difference in neuraminidase between the pregnancies and the child-bearings （ P 〉 0.05 ）. The amount of Lactobacillus was higher in child-bearing women, which was significant different from the pregnancy group （ P 〈 0.01 ）. The content of E. coli was lower in the child-bearings compared with the pregnancies, and the difference was significant （P 〈 0.05 ）. The difference of Gardnerella vaginalis between the two groups was insignificant （ P 〉 0.05 ）. Conclusion The differences of vaginal microecology between the pregnancy group and child-bearing group is relevant to the levels of estrogen and progestogen.