Antimutagenic effect of heteroxylans,arabinogalactans, pectins and mannans in the Euglena assay |
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| Authors: | Belicová A Ebringer L Kraj?ovi? J Hromádková Z Ebringerová A |
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| Institution: | (1) Institute of Cell Biology, Faculty of Natural Sciences, Comenius University, Odborárske nám. 5, 811 07 Bratislava, Slovak Republic;(2) Institute of Chemistry, Slovak Academy of Sciences, Dúbravská cesta 9, 842 38 Bratislava, Slovak Republic |
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| Abstract: | A series of plant cell wall polysaccharides – heteroxylans, arabinogalactans, pectins and mannans exerted antimutagenic (antibleaching) activity against acridine orange- and ofloxacin-induced mutagenicity in the Euglena assay. All polysaccharides tested exhibited a significant dose-dependent antibleaching activity and the percentage inhibition of mutagenicity ranged from 52 to 96%. It can be assumed that the antimutagenicity of the polysaccharides depends on their structural and compositional properties as well as on the different mode of action of both the mutagens tested. |
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| Keywords: | Acridine orange antimutagenicity Euglena gracilis ofloxacin polysaccharides |
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