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FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16INK4a increase |
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| Authors: | Jessica Voisin Francesca Farina Swati Naphade Morgane Fontaine Kizito‐Tshitoko Tshilenge Carlos Galicia Aguirre Alejandro Lopez‐Ramirez Julia Dancourt Aurélie Ginisty Satish Sasidharan Nair Kuruwitage Lakshika Madushani Ningzhe Zhang Fran?ois‐Xavier Lejeune Marc Verny Judith Campisi Lisa M. Ellerby Christian Neri |
| Affiliation: | 1.Centre National de la Recherche Scientifique UMR 8256, Institut National de la Santé et de la Recherche Médicale ERL U1164, Assistance Publique‐Hôpitaux de Paris, Brain‐C Lab, Sorbonne Université, ParisFrance;2.Buck Institute for Research on Aging, NovatoCA, USA;3.Lawrence Berkeley National Laboratory, BerkeleyCA, USA |
| Abstract: | |
| Keywords: | neurodegenerative disease neuronal differentiation neuronal senescence response mechanisms temporal dynamics |