The stilbene derivatives,nucleosides, and nucleosides modified by stilbene derivatives |
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Institution: | 3. Fondation for Neglected Disease Research, Yelahanka, Bangalore 562157, India;1. Department of Chemistry, University College London, 20 Gordon St, London WC1H 0AJ, UK;2. Department of Chemistry, 1155 Union Circle Drive #305070, University of North Texas, Denton, TX 76203-5017, USA |
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Abstract: | In this short review, including 187 references, the issues of biological activity of stilbene derivatives and nucleosides and the biological and medicinal potential of fusion of these two classes are discussed. The stilbenes, especially the stilbenoids, and nucleosides are both biologically active. Hybrids formed from binding of these compounds have not yet been broadly studied. However, those that have been investigated exhibit desirable medicinal properties. The review is divided in such parts: I. Derivative of stilbene (biomedical investigations, biological activities in cells, enzymes and hazard), parts II. naturally occurred nucleoside and its derivatives: uridine, thymidine and 5-methyluridine, cytidine, adenosine, guanosine and part III. hybrid molecules- drugs and hybrid molecules- nucleoside - stilbene and its derivative. |
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Keywords: | Nucleoside Derivative of stilbene Stilbene Nucleoside hybrids |
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