Numerical modelling of blood clot extraction by aspiration thrombectomy. Evaluation of aspiration catheter geometry |
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| Institution: | 2. Department of Cerebrovascular Medicine, Saga-Ken Medical Centre Koseikan, Saga, Japan;3. Department of Neurology, Saga-Ken Medical Centre Koseikan, Saga, Japan;2. Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, USA;3. School of Medicine, University of Michigan, Ann Arbor, Michigan, USA;4. Mechanical Engineering, Worcester Polytechnic Institute, Worcester, Massachusetts, USA;5. Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA |
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| Abstract: | Aspiration thrombectomy is one of the most effective systems for blood clot removal and vessel recanalization. We present the results of a study involving the modelling and extraction of blood clots in the arteries of the human body using the following computer tools: Bond-Graph methodology for the fluid domain and Multi-Body Simulation for the mechanical domain. The modelling for the mechanical domain focuses on the clot and the distal end section of an aspiration device. Our final model considers an elastic characterization of the blood clot with progressive detachment from the vessel wall. We conclude that the results of such modelling could potentially improve the effectiveness of blood clot removal by reducing the risk of clot fragmentation. Such modelling could also potentially provide an adjunct technique in improving recanalization of arteries over a range of given parameters (mechanical properties of the vessel, mechanical properties of the blood clot, blood clot length, suction pressure, catheter – clot distance, catheter shape, catheter diameter and vessel occlusion). |
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| Keywords: | Blood clot removal Aspiration thrombectomy device Stroke Bond-graph Multi-body |
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