Mechanical effects of load speed on the human colon |
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| Institution: | 1. Emergency Surgery Unit, University Hospital of Nice, CHU de Nice Hôpital Pasteur 2, Université de Nice Sophia-Antipolis, France;2. Biomechanical Applied Laboratory, UMRT24, IFSTTAR, Aix-Marseille University, France;3. Department of Visceral Surgery, AP-HM Hôpital Nord, Aix-Marseille University, France;1. GIOME and the Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, China;2. Yiducloud (Chongqing) Technology Co., Ltd., Chongqing 400044, China;3. Giome Academia, Department of Clinical Medicine, Aarhus University, 8200 Aarhus N, Denmark;4. GIOME, Department of Surgery, The Chinese University of Hong Kong, Hong Kong;1. Technical University of Munich, 85748 Garching, Germany;2. Universität Tübingen, 72076 Tübingen, Germany;1. Department of Industrial Engineering, University of Padova, Italy;2. Centre for Mechanics of Biological Materials, University of Padova, Italy;3. IFSO Bariatric Centre of Excellence, Policlinico Universitario, University of Padova, Italy;4. Department of Surgery, Oncology and Gastroenterology, University of Padova, Italy |
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| Abstract: | The aim of this study was to examine the mechanical behavior of the colon using tensile tests under different loading speeds.Specimens were taken from different locations of the colonic frame from refrigerated cadavers. The specimens were submitted to uniaxial tensile tests after preconditioning using a dynamic load (1 m/s), intermediate load (10 cm/s), and quasi-static load (1 cm/s).A total of 336 specimens taken from 28 colons were tested. The stress-strain analysis for longitudinal specimens indicated a Young’s modulus of 3.17 ± 2.05 MPa under dynamic loading (1 m/s), 1.74 ± 1.15 MPa under intermediate loading (10 cm/s), and 1.76 ± 1.21 MPa under quasi-static loading (1 cm/s) with p < 0.001. For the circumferential specimen, the stress-strain curves indicated a Young’s modulus of 3.15 ± 1.73 MPa under dynamic loading (1 m/s), 2.14 ± 1.3 MPa under intermediate loading (10 cm/s), and 0.63 ± 1.25 MPa under quasi-static loading (1 cm/s) with p < 0.001. The curves reveal two types of behaviors of the colon: fast break behavior at high speed traction (1 m/s) and a lower break behavior for lower speeds (10 cm/s and 1 cm/s). The circumferential orientation required greater levels of stress and strain to obtain lesions than the longitudinal orientation. The presence of taeniae coli changed the mechanical response during low-speed loading.Colonic mechanical behavior varies with loading speeds with two different types of mechanical behavior: more fragile behavior under dynamic load and more elastic behavior for quasi-static load. |
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| Keywords: | Colonic mechanical response Human colon Biomechanics Uniaxial solicitation |
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