Ribosome bound RNA-dependent RNA polymerase: changes in total and specific activity during maturation of avian erythrocytes.

Ribosome bound RNA-dependent RNA polymerase activity from immature chicken erythrocytes was shown to be predominantly primer-dependent, in contrast to the template-dependent synthesis demonstrated by previous workers (4). During the maturation of the immature avian erythrocyte, the total and specific activities of this ribosome bound enzyme preparation increase 40 and 9.4 times respectively.