BK channels: the spring between sensor and gate |
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Authors: | Papazian Diane M |
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Affiliation: | Department of Physiology and Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095, USA. |
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Abstract: | K+ channels contain two main functional domains, an ion-selective pore and a sensor that determines whether the cytoplasmic pore gate is open or closed. In this issue of Neuron, Niu et al. provide compelling evidence that the link between sensor and gate is a remarkably simple mechanical spring. |
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