Breaching the great wall: peptidoglycan and microbial interactions |
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Authors: | Cloud-Hansen Karen A Peterson S Brook Stabb Eric V Goldman William E McFall-Ngai Margaret J Handelsman Jo |
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Affiliation: | Department of Plant Pathology, University of Wisconsin, 1630 Linden Drive, Madison, Wisconsin 53706, USA. |
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Abstract: | Once thought to be a process that occurred only in a few human pathogens, release of biologically active peptidoglycan fragments during growth by Gram-negative bacteria controls many types of bacterial interaction, including symbioses and interactions between microorganisms. This Perspective explores the role of peptidoglycan fragments in mediating a range of microbial-host interactions, and discusses the many systems in which peptidoglycan fragments released during bacterial growth might be active. |
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