Synthesis and antibacterial activity of oxazolidinone containing sulphonyl group |
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| Authors: | Cui Yingjie Yang Yushe Chen Kaixian Ji Ruyun Zhang Shuhua |
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| Affiliation: | Shanghai Institute of Materia Medica, Shanghai Institute for Biological Science, Chinese Academy of Sciences, 200031, Shanghai, China. |
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| Abstract: | A series of oxazolidinone derivatives carrying sulphonyl group was synthesized and their antibacterial activity was evaluated in vitro. Many of such compounds demonstrated potent antibacterial activity. The activity of a novel compound (YC-20) was 2-4-fold more potent than that of linezolid. |
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