Continuous production of N-(benzyloxycarbonyl)-L-glycyl-L-phenylalanine methyl ester utilizing extractive reaction in aqueous/organic biphasic medium |
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| Authors: | Murakami Y Oda T Chiba K Hirata A |
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| Institution: | Department of Chemical Engineering, Waseda University, Tokyo, Japan. |
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| Abstract: | N-(Benzyloxycarbonyl)-L-glycyl-L-phenylalanine methyl ester was continuously synthesized, enzymatically, utilizing an extractive reaction in an aqueous/organic biphasic system. The extremely high yield, ca. 100%, was obtained continuously in a water/butyl acetate biphasic medium. |
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