Transposon Tn7 directs transposition into the genome of filamentous bacteriophage M13 using the element-encoded TnsE protein |
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Authors: | Finn Jessica A Parks Adam R Peters Joseph E |
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Institution: | Department of Microbiology, Cornell University, Ithaca, NY 14853, USA. |
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Abstract: | The bacterial transposon Tn7 has a pathway of transposition that preferentially targets conjugal plasmids. We propose that this same transposition pathway recognizes a structure or complex found during filamentous bacteriophage replication, likely by targeting negative-strand synthesis. The ability to insert into both plasmid and bacteriophage DNAs that are capable of cell-to-cell transfer would help explain the wide distribution of Tn7 relatives. |
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