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Application of bioreactor design principles and multivariate analysis for development of cell culture scale down models |
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| Authors: | Lia Tescione James Lambropoulos Madhava Ram Paranandi Helena Makagiansar Thomas Ryll |
| Institution: | 1. +617 679 2270+617 679 3415;2. Biogen Idec, Cell Culture Development, Cambridge, Massachusetts |
| Abstract: | |
| Keywords: | scale down model bioreactor design scale up multivariate analysis process characterization quality by design |