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基于CdSe-ZnS量子点的PDT体外灭活 HL60最佳实验参数的研究
引用本文:黄康强,刘堃,熊建文,黄一睿. 基于CdSe-ZnS量子点的PDT体外灭活 HL60最佳实验参数的研究[J]. 激光生物学报, 2011, 20(4): 548-552,483. DOI: 10.3969/j.issn.1007-7146.2011.04.022
作者姓名:黄康强  刘堃  熊建文  黄一睿
作者单位:1. 广东省高等学校量子信息技术重点实验室,华南师范大学物理与电信工程学院,广东广州510006
2. 韶关学院物理学院,广东韶关,512005
基金项目:国家自然科学基金资助项目(61072029); 广东省自然科学基金资助项目(10151063101000025); 广州市科技计划资助项目(2010Y1-C111)
摘    要:随着光动力学疗法( photodynamic therapy,PDT)基础研究的不断深入和临床应用的广泛开展,根据患者的个体差异寻求高性能的光敏剂和精确量化光动力剂量,已成为亟待解决的难题,并日渐成为PDT研究的热点.以ZnS包裹的CdSe量子点(CdSe-ZnS)作为光敏剂,以人前髓细胞(早幼细胞)株HI6O为研究对...

关 键 词:量子点(CdSe-ZnS)  光敏剂  光动力疗法(PDT)  HL60  CCK-8  PDT效率

Experiment Research on the Best Parameters of the Vitro Destruction of HL60 Cells by the Use of QDs(CdSe-ZnS)-based Photodynamic Therapy
HUANG Kangqiang,LIU Kun,XIONG Jianwen,HUANG Yirui. Experiment Research on the Best Parameters of the Vitro Destruction of HL60 Cells by the Use of QDs(CdSe-ZnS)-based Photodynamic Therapy[J]. ACTA Laser Biology Sinica, 2011, 20(4): 548-552,483. DOI: 10.3969/j.issn.1007-7146.2011.04.022
Authors:HUANG Kangqiang  LIU Kun  XIONG Jianwen  HUANG Yirui
Affiliation:HUANG Kangqiang~1,LIU Kun~2,XIONG Jianwen~(1*),HUANG Yirui~1 (1.Laboratory of Quantum Information Technology,School of Physics and Telecommunication Engineering,South China Normal University,Guangzhou 510006,Guangdong,China,2.School of Physics,Shaoguan University,Shaoguan 512005,China)
Abstract:As PDT techniques continue to develop and find more potential clinical indications,seeking for a high-performance photosensitizer and accurate dosimetry of PDT has become a critical and challenging goal for achieving satisfied individual treatments,and is becoming a hot spot of PDT research.CdSe coated with ZnS quantum dots(CdSe-ZnS) was adopted as a photosensitizer.The leukaemia cells HL60 was carried an experimental research in photodynamic therapy (PDT) based on QDs(CdSe-ZnS) by the use of our PDT reacti...
Keywords:QDs(CdSe-ZnS)  photosensitizer  photodynamic therapy(PDT)  HL60  CCK-8  PDT efficiency  
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