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Skeletal Metastases in Pancreatic Cancer: A Retrospective Study and Review of the Literature
Authors:Mitesh J. Borad   Hamid Saadati   Arun Lakshmipathy   Elizabeth Campbell   Patricia Hopper   Gayle Jameson   Daniel D. Von Hoff     M. Wasif Saif
Abstract:Background: Skeletal metastases represent an underappreciated site of metastasis in patients with pancreatic cancer. Previous reports have estimated the prevalence to range from 5 percent to 20 percent. With the use of gemcitabine and novel targeted agents such as erlotinib, there has been a modest increase in survival in patients with advanced pancreatic cancer. As such, it is anticipated that previously uncommon occurrences such as skeletal metastases will become more frequent.
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