原发性高血压和卒中患者的正常血压子女白细胞钠钾含量的观察

本文报道对原发性高血压患者子女38例、卒中患者子女14例及健康家族子女23例白细胞钠钾含量测定的结果。三组均为正常血压者,高血压患者子女组的白细胞钠含量较低、钾含量较高,且在不同性别、不同高血压家族史间比较,亦存在差别。卒中患者子女组的白细胞钠钾含量无显著变化,虽他们的舒张压显著高于对照组。本文就上述结果产生的可能机制及其与高血压、卒中发病的关系进行了讨论。

OBSERVATIONS ON LEUCOCYTE SODIUM AND POTASSIUM CONTENT IN YOUNG NORMOTENSIVES WITH FAMILY HISTORY OF HYPERTENSION AND/OR STROKE

Sodium and potassium content of isolated leucocytes was determined in youngnormotensives with different family histories of hypertension and/or stroke.Theresults showed that the sodium content was lower and potassium content was higherin 38 persons with family history of hypertension in comparison with 23 personswithout family history of hypertension.Such differences were more marked in malesubjects and those having both hypertensive parents.Leucocyte sodium and potas-sium content in 14 persons born of stroke parents was not different from that withoutfamily history of hypertension and/or stroke,but the blood pressure level tendedto be higher in the former than in the latter.Possible mechanism underlying thementioned changes and its link in the pathogenesis of hypertension and stroke werediscussed.