Control of high affinity lectin binding to an integral membrane glycoprotein in lipid bilayers |
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| Authors: | Nika V. Ketis Chris W.M. Grant |
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| Affiliation: | Department of Biochemistry, University of Western Ontario, London, Ontario, N6A 5C1 Canada |
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| Abstract: | High affinity binding of wheat germ agglutinin to glycophorin is demonstrated to be potently affected by non-specific interaction of the receptor with other protein and oligosaccharide structures present at the membrane surface. It is suggested that this may represent a significant general mechanism of receptor control. |
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| Keywords: | Glycophorin Lectin (Wheat germ agglutinin) |
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