Sodium uptake mechanisms in brush-border membrane vesicles prepared from rabbit renal cortex |
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| Authors: | David G. Warnock Victoria J. Yee |
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| Affiliation: | Division of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 U.S.A. |
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| Abstract: | Amiloride-sensitive and amiloride-insensitive components of 22Na+ uptake were examined in brush-border membrane vesicles prepared from rabbit renal cortex. Both components could be stimulated by interior-negative electrical potentials, demonstrating a sodium conductance pathway and an effect of electrical potential on the initial rate of Na+/H+ exchange. |
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| Keywords: | Amiloride Conductance pathway Valinomycin (Rabbit renal brush-border membrane vesicles) Hepes |
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