Water diffusion under osmotic gradients in frog gastric mucosa |
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Authors: | Leopoldo Villegas |
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Affiliation: | Centro de Biofisica y Bioquímica, Instituto Venezolano de Investigaciones Cientificas (IVIC), Apartado 1827, Caracas 1010A Venezuela |
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Abstract: | The asymmetry of the osmotic response of the frog gastric mucosa has been further analyzed by studying the effect of external tonicity changes on the water diffusion fluxes. Hyperosmotic solution at the serosal surface does not affect the water diffusion fluxes. Hyperosmotic solution at the mucosal surface, with isosmotic solution at the serosal surface, significantly reduces (P<0.001) the serosal-to-mucosal and the mucosal-to-serosal water diffusion. An increment in the restriction offered by the mucosa to water diffusion by effect of hypertonicity at the mucosal surface is proposed. |
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Keywords: | Water diffusion Osmotic gradient Asymmetric response (Frog gastric mucosa) |
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