Release of mitochondrial respiratory control by cyanate salts |
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Authors: | Wendy Cammer |
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Affiliation: | The Saul R. Korey Department of Neurology and the Department of Neuroscience, Albert Einstein College of Medicine, 1300 Morris Park Avenue, F-140, Bronx, NY 10461 USA |
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Abstract: | Mitochondrial respiration is stimulated by 5–40 mM potassium cyanate in the presence or absence of oligomycin. When the cyanate concentration is increased over 40 mM, the mitochondria respire at progressively lower rates. In these respects, although at relatively high concentrations, cyanate behaves as an uncoupler of oxidative phosphorylation. |
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Keywords: | Cyanate Oxidative phosphorylation Uncoupler Demyelination Respiration (Mitochondria) |
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