Search for the determinants of allergenicity in proteins of the lipocalin family |
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Authors: | Juha Rouvinen Tuomas Virtanen Rauno Mntyjrvi |
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Institution: | Juha Rouvinen, Tuomas Virtanen,Rauno Mäntyjärvi |
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Abstract: | Three different lines of analysis have been applied to approach the problem of the allergenicity of certain proteins: biological functions, molecular structures and immunological properties. It is immediately obvious that these three are interdependent. The lipocalin family of proteins includes a significant number of allergens. A considerable amount of data is already available of lipocalins and some insights about allergenic determinants can now be presented. However, more information on the molecular structures and immunological parameters of lipocalin allergens is required. |
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Keywords: | Lipocalin proteins Epitopes |
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