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Human colorectal cancer cells efficiently conjugate the cyclopentenone prostaglandin,prostaglandin J2, to glutathione
Authors:Brian Cox  Laine J Murphey  William E Zackert  Rebecca Chinery  Ramona Graves-Deal  Olivier Boutaud  John A Oates  Robert J Coffey  Jason D Morrow
Affiliation:1. Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-6602, USA;2. Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232-6602, USA;3. Department of Medicine, Mayo Medical School, Rochester, MN 55905, USA
Abstract:
Keywords:Prostaglandin  Cyclopentenone  Colorectal cancer  Glutathione adduct  Eicosanoid  Lipid  PG  prostaglandin  PPAR  peroxisome proliferator-activated receptor  GSH  glutathione  COX-2  cyclooxygenase-2  LC  liquid chromatography  MS  mass spectrometry  HPLC  high pressure liquid chromatography  GC  gas chromatography  CID  collision-induced dissociation
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