Trees on networks: resolving statistical patterns of phylogenetic similarities among interacting proteins |
| |
| Authors: | William P Kelly Michael PH Stumpf |
| |
| Affiliation: | (1) Centre for Bioinformatics, Imperial College, London, UK;(2) Centre for Integrative Systems Biology at Imperial College (CISBIC), London, UK;(3) Institute of Mathematical Sciences, Imperial College, London, UK |
| |
| Abstract: | Background Phylogenies capture the evolutionary ancestry linking extant species. Correlations and similarities among a set of species are mediated by and need to be understood in terms of the phylogenic tree. In a similar way it has been argued that biological networks also induce correlations among sets of interacting genes or their protein products. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
