It takes two to Get3 |
| |
| Authors: | Sinning Irmgard Bange Gert Wild Klemens |
| |
| Affiliation: | Heidelberg University Biochemistry Center, INF 328, 69120 Heidelberg, Germany. irmi.sinning@bzh.uni-heidelberg |
| |
| Abstract: | Tail-anchored (TA) membrane proteins perform essential cellular functions. They are posttranslationally inserted into the endoplasmic reticulum (ER) membrane by interaction of the Get3 chaperone with the Get1/2 receptor. Two independent structural and functional analyses of the Get3/receptor complex by Stefer et?al. and Mariappan et?al. now provide insights into TA protein insertion. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
