Glycosylation of rat liver cytochrome on the ribosomal level |
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Authors: | Åke Elhammer Gustav Dallner Tsuneo Omura |
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Institution: | 1. Department of Biochemistry, Arrhenius Laboratory, University of Stockholm, Stockholm, Sweden;2. Department of Pathology at Huddinge Hospital, Karolinska Institutet, Stockholm, Sweden;3. Department of Biology, Faculty of Science, Kyushu University, Fukuoka, Japan |
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Abstract: | The distribution and site of synthesis of cytochrome was studied by antibody precipitation of the enzyme labeled . The enzyme is present in rough and smooth microsomes, Golgi and outer mitochondrial membranes. The cytochrome is synthesized only on bound ribosomes, where glucosamine and galactose moieties are also added. The enzyme seems to be devoid of mannose and sialic acid residues. |
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