Optimum interaction of sterol side chains with phosphatidylcholine |
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| Authors: | Iain F. Craig George S. Boyd Keith E. Suckling |
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| Affiliation: | Department of Biochemistry, University of Edinburgh Medical School, Teviot Place, Edinburgh EII8 9AG U.K. |
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| Abstract: | The specificity of the interaction between the cholesterol side chain and egg phosphatidylcholine was precisely defined by examining the effect of three new analogues of cholesterol with modified side chains on the ordering of two steroid spin labels in liposomes. The complete side chain of cholesterol was shown to be required for maximum ordering. Sterols with side chains shorter or longer than cholesterol caused significantly less ordering. |
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