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Chiisanoside is not absorbed but inhibits oil absorption in the small intestine of rodents
Authors:Yoshizumi Kazuma  Murota Kaeko  Watanabe Shiro  Tomi Hironori  Tsuji Tomoko  Terao Junji
Institution:Research Institute, Fundamental Research Faculty, Fancl Corporation, Yokohama, Kanagawa 244-0806, Japan.
Abstract:Chiisanoside is the main component of Acanthopanax sessiliflorus leaves. Simultaneous administration of chiisanoside resulted in a decrease in the plasma TG level and increase of undigested TG in the intestinal lumen after oil gavage to mice. This suggests that chiisanoside has the potential to prevent obesity as a lipase inhibitor which suppresses fat absorption in vivo.
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