Directed evolution of microbial oxidative enzymes |
| |
Authors: | Cherry J R |
| |
Affiliation: | Product Improvement Group, Novo Nordisk Biotech, Inc., Davis, CA 95616, USA. cherry@nnbt.com |
| |
Abstract: | In the past year, a number of oxidative enzymes have been the target of directed evolution. Catalase reaction specificity has been shifted to peroxidase, the high pH, thermal and oxidative stability of a fungal peroxidase has been dramatically improved, and the substrate specificity of cytochrome P450 has been altered to include substrates that the wild-type enzymes are incapable of oxidizing. |
| |
Keywords: | |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|