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Prenylated isoflavonoids from Millettia pervilleana
Authors:Palazzino Giovanna  Rasoanaivo Philippe  Federici Elena  Nicoletti Marcello  Galeffi Corrado
Institution:Laboratorio di Chimica del Farmaco, Istituto Superiore di Sanità, V. le Regina Elena 299, I-00161 Rome, Italy. palazzin@iss.it
Abstract:From the root bark of Millettia pervilleana, which had shown significant cytotoxic activity, a 3-phenylcoumarin, named pervilleanine, two new pterocarpans, pervilline and pervillinine, and one known, emoroidocarpan, were isolated in addition to rotenone and 3alpha-hydroxyrotenone. The anticancer activity of two previously isolated isoflavanones, pervilleanone and 3'-O-demethylpervilleanone is reported.
Keywords:Millettia pervilleana  Leguminosae  Coumarins  Pervilleanine  Pterocarpans  Pervilline  Pervillinine  Cytotoxic and anti-cancer activity
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