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昆虫病毒的增强蛋白
引用本文:胡薇,黎路林,洪华珠. 昆虫病毒的增强蛋白[J]. 生物化学与生物物理进展, 1996, 23(1): 20-24
作者姓名:胡薇  黎路林  洪华珠
作者单位:华中师范大学昆虫学研究所;华中师范大学昆虫学研究所;华中师范大学昆虫学研究所
摘    要:在某些昆虫病毒的包涵体中相继发现了增强蛋白.这类蛋白可以增强核型多角体病毒对昆虫幼虫及体外培养的昆虫细胞的感染力,缩短杀虫时间,提高杀虫效率;还可以增强其他生物杀虫剂(如:Bt)的毒力.关于增强蛋白的作用机制有两种观点:降解围食膜以利于病毒粒子侵染细胞或直接作用于细胞质膜促进病毒粒子的套膜与之融合.该蛋白是由病毒编码的,现已克隆出第一个增强蛋白基因,该基因含有一个2703bP的开放阅读框,其核苷酸序列分析业已完成.增强蛋白的发现有望对病毒杀虫剂的推广产生积极影响.

关 键 词:杆状病毒   增强蛋白   增效作用
收稿时间:1995-01-03
修稿时间:1995-03-13

The Enhancing Proteins of Baculovirus
Hu Wei,Li Lulin and Hong Huazhu. The Enhancing Proteins of Baculovirus[J]. Progress In Biochemistry and Biophysics, 1996, 23(1): 20-24
Authors:Hu Wei  Li Lulin  Hong Huazhu
Affiliation:Institute ofEntomology, Centre China Normal University;Institute ofEntomology, Centre China Normal University;Institute ofEntomology, Centre China Normal University
Abstract:Several enhancing proteins (enhancins) were isolated from the inclusion bodies of some insect viruses. The proteins can enhance the infection of NPV both in vitro and in vivo. There are two hypotheses about the mechanism of enhancement: disrupting the peritrophic membrane (PM ) and facilitating the penetration of virions or increasing the attachment and fusion between the virion envelope and the midgut cell membrane. The proteins are encoded by virus. The first enhancin gene has been cloned and sequenced.Since enhancins can shorten the life-span of infected larvae and increased the effectiveness of biopesticides, it will stimulate the widespread application of viral pesticides.
Keywords:baculovirus   enhancins   synergism
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