Ability of formyl-methionyl-tRNA to initiate globin synthesis in the presence of double-stranded RNA or in the absence of hemin |
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Authors: | Frederick Cahn Martin Lubin |
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Institution: | 1. Dept. of Microbiology, Dartmouth Medical School, 03755, Hanover, N.H., USA
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Abstract: | Initiation of protein synthesis by endogenous methionyl-tRNA in rabbit reticulocyte lysates is strongly inhibited when double-stranded RNA is added to, or hemin omitted from, the incubation mixture, but initiation by formyl-methionyl-tRNA is relatively uninhibited. |
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