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<Emphasis Type="Italic">Streptomyces</Emphasis> metabolites in divergent microbial interactions
Authors:Hideaki Takano  Tatsuya Nishiyama  Sho-ichi Amano  Teruhiko Beppu  Michihiko Kobayashi  Kenji Ueda
Institution:1.Life Science Research Center, College of Bioresource Sciences,Nihon University,Fujisawa,Japan;2.Institute of Applied Biochemistry and Graduate School of Life and Environmental Sciences,University of Tsukuba,Tsukuba,Japan
Abstract:Streptomyces and related bacteria produce a wide variety of secondary metabolites. Of these, many compounds have industrial applications, but the question of why this group of microorganism produces such various kinds of biologically active substances has not yet been clearly answered. Here, we overview the results from our studies on the novel function and role of Streptomyces metabolites. The diverged action of negative and positive influences onto the physiology of various microorganisms infers the occurrence of complex microbial interactions due to the effect of small molecules produced by Streptomyces. The interactions may serve as a basis for the constitution of biological community.
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