Radioimmunoassay of plasma oestriol |
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Authors: | E Youssefnejadian I F Sommerville |
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Affiliation: | Department of Biochemical Endocrinology, Chelsea Hospital for Women, Dovehouse Street, London, S.W. 3; and Institute of Obstetrics and Gynaecology, University of London, London, England |
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Abstract: | A relatively specific antiserum to oestriol-16-17-dihemisuccinate-bovine serum albumin was raised in white New Zealand rabbits and a radioimmunological method developed for the quantitative determination of ether-extractable oestriol in the peripheral venous plasma (0.1 ml) of pregnant women. The method has been evaluated and applied to the determination of plasma oestriol in 400 blood samples collected from women with uncomplicated pregnancies. |
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