Lectin-binding studies of a human skin mastocytoma |
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| Authors: | Udo Schumacher Hans-Peter Horny Ulrich Welsch Edwin Kaiserling |
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| Affiliation: | (1) Department of Anatomy, University of Munich, Pettenkofer Strasse 11, D-8000 Munich, W. Germany;(2) Department of Pathology, University of Tübingen, Tübingen, W. Germany |
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| Abstract: | Summary A solitary mastocytoma of the skin was investigated to assess the lectin-binding pattern of human mast cells. Of 18 Fluorescein-labelled lectins tested, nine reacted with mast cell granules. While lectins recognizingN-acetylgalactosamine or fucose residues did not stain mast cells, lectins with binding sites forN-acetylglucosamine,  -methyl mannopyranoside, galactose, complex carbohydrates ofN-acetyl-lactosamine type and sialic acid gave a positive reaction. |
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