Synthesis of fluorinated analogues of SJG-136 and their DNA-binding potential |
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| Authors: | Kamal Ahmed Reddy P S M M Reddy D Rajasekhar Laxman E Murthy Y L N |
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| Affiliation: | Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500007, India. ahmedkamal@ins.iictnet.com |
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| Abstract: | A series of C2-exo-fluorounsaturated pyrrolobenzodiazepines (PBDs) have been synthesized. These C2-exo-fluorounsaturated PBD dimers have exhibited remarkable DNA-binding affinity. |
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