Revised structures of daturalactone and 12-oxowithanolide |
| |
Authors: | Ashok K Kalla ML Raina KL Dhar MA Qurishi G Snatzke |
| |
Affiliation: | 1. Regional Research Laboratory, Jammu-180001, India;2. Ruhr-Universität, Abteilung für Chemie, D-4630 Bochum 1, W. Germany |
| |
Abstract: | Recently Dhar et al. reported the isolation of two new steroidal lactones from the leaves of Datura quercifolia HBK and formulated them as 5α,12α,17α-trihydroxy-1-oxo-6α, 7α-epoxy-22 S-witha-2,24-dienolide and 5α,17α-dihydroxy-1, 12-dioxo-6α,7α-epoxy-22 S-witha-2,24-dienolide on the basis of UV, IR, NMR and MS studies. Further detailed chemical and spectral studies have led to revised structures, namely 5α, 12α-dihydroxy-1-oxo-6α,7α: 24α, 25α-diepoxy-20 S, 22 R-with-2-enolide and 5α-hydroxy-1, 12-dioxo-6α, 7α: 24α, 25α-diepoxy-20 S, 22 R-with-2-enolide, respectively, for the above two compounds. |
| |
Keywords: | Solanaceae withanolides revised structures daturalactone 12-oxowithanolide |
本文献已被 ScienceDirect 等数据库收录! |
|