虚拟导航支气管镜联合EBUS-GS技术在直径≤2 cm的肺外周结节诊断中的应用

摘要 目的：探究虚拟导航支气管镜联合EBUS-GS技术在直径≤2 cm的肺外周结节诊断中的诊断价值。方法：本研究采用回顾性分析的方法，选取2019年5月-2022年5月期间在我院就诊的140例直径≤2 cm的肺外周结节患者作为研究对象，随机分为对照组和实验组，各70例。对照组使用传统支气管镜技术进行诊断，实验组使用虚拟导航支气管镜联合EBUS-GS技术进行诊断，并进行随访实验。记录并比较两组患者的可视率、操作时间、诊断率及并发症发生率等指标。结果：对照组和实验组中的病灶位置比较，两组差异无统计学意义（P>0.05）。实验组与对照组病变大小相比差异无统计学意义（P>0.05），实验组可视率高于对照组。对照组和实验组的支气管镜操作总时间比较，无明显统计学差异（P>0.05），探及病灶位置时间与对照组相比，实验组低于对照组（P<0.05）。实验组中恶性病变的诊断率为89.74%，良性肺结节的诊断率为83.87%，而对照组恶性病变的诊断率为60%，良性结节的诊断率为50%，两组间病变性质的良性和恶性诊断率相比较，差异均具有统计学意义（P<0.05）。与对照组相比，实验组不良反应发生率2.86%低于对照组不良反应发生率18.57%，差异具有统计学意义（P<0.05）。结论：虚拟导航支气管镜联合EBUS-GS技术是一种可行且有效的方法，可用于直径≤2 cm的肺外周结节的诊断。该技术既可提高诊断准确性，又可减少不必要的切除手术，对患者具有重要的临床意义。

Application of Virtual Navigation Bronchoscopy Combined with EBUS-GS Technology in the Diagnosis of Peripheral Pulmonary Nodules with a Diameter of ≤2 cm

ABSTRACT Objective: To explore the diagnostic value of virtual navigation bronchoscopy combined with EBUS-GS technology in the diagnosis of peripheral pulmonary nodules with a diameter of ≤ 2 cm. Methods: This study used a retrospective analysis method and selected 140 patients with peripheral pulmonary nodules with a diameter of ≤ 2 cm who visited our hospital from May 2019 to May 2022 as the study subjects. They were randomly divided into a control group and an experimental group, with 70 patients in each group. The control group was diagnosed using traditional bronchoscopy technology, while the experimental group was diagnosed using virtual navigation bronchoscopy combined with EBUS-GS technology, and follow-up experiments were conducted. Record and compare indicators such as visual acuity, surgical time, diagnostic rate, and incidence of complications between the two groups of patients. Results: There was no statistically significant difference in the location of lesions between the control group and the experimental group (P>0.05). There was no statistically significant difference in lesion size between the experimental group and the control group (P>0.05), and the visual acuity of the experimental group was higher than that of the control group. There was no significant statistical difference (P>0.05) in the total time of bronchoscopy between the control group and the experimental group. Compared with the control group, the experimental group had a lower time to detect the location of the lesion (P<0.05). The diagnostic rate of malignant lesions in the experimental group was 89.74%, and the diagnostic rate of benign pulmonary nodules was 83.87%. However, the diagnostic rate of malignant lesions in the control group was 60%, and the diagnostic rate of benign nodules was 50%. The difference in the diagnostic rates of benign and malignant lesions between the two groups was statistically significant (P<0.05). Compared with the control group, the incidence of adverse reactions in the experimental group was 2.86% lower than that in the control group, which was 18.57%, with a statistically significant difference (P<0.05). Conclusion: Virtual navigation bronchoscopy combined with EBUS-GS technology is a feasible and effective method for the diagnosis of peripheral pulmonary nodules with a diameter of ≤ 2 cm. This technology can improve diagnostic accuracy and reduce unnecessary resection surgeries, which has important clinical significance for patients.