Experimental vaccination of rainbow trout against Loma salmonae using a live low-virulence variant of L. salmonae |
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Authors: | J. G. Sá nchez,D. J. Speare,,R. J. F. Markham, S. R. M. Jones |
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Affiliation: | Department of Pathology and Microbiology, Atlantic Veterinary College–UPEI, 550 University Avenue, Charlottetown, PEI, C1A 4P3, Canada |
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Abstract: | Prior exposure of rainbow trout Oncorhynchus mykiss juveniles to the low-virulence variant of Loma salmonae, L. salmonae SV, spores resulted in a xenoma intensity in the gill filaments fourteen times lower (0·044 v. 0·641 xenomas per filament; P=0·0001) than that observed in the naive controls, challenged with L. salmonae spores, as determined morphometrically by in situ hybridization at the peak of the disease (between 4 and 6 weeks post exposure). The marked degree of reduction in numbers of xenomas that formed after challenge suggests that use of the low-virulence variants should be further considered as a means to protect fish in regions where the parasite is endemic, to protect them during grow out periods. |
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Keywords: | fish microsporidia experimental vaccination Loma salmonae |
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