| 胍基丁胺在成年大鼠组织中的表达和分布 |
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| 引用本文： | 蒋春华,项德坤,黄庆愿,高钰琪. 胍基丁胺在成年大鼠组织中的表达和分布[J]. 中国组织化学与细胞化学杂志, 2009, 18(6): 696-700. DOI: 10.3870/zgzzhx.2009.06.017 |
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| 作者姓名： | 蒋春华 项德坤 黄庆愿 高钰琪 |
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| 作者单位： | 第三军医大学高原军事医学系病理生理学与高原生理学教研室;高原医学教育部重点实验室;全军高原生理与高原病研究重点实验室,重庆,400038 |
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| 摘 要： | 目的观察胍基丁胺（agmatine,AGM）在成年Wistar大鼠全身组织的表达和分布。方法采用免疫组织化学法,用自制的抗胍基丁胺多克隆抗体检测胍基丁胺在成年Wistar大鼠全身组织中的表达分布情况。结果胍基丁胺在胃、十二指肠、空肠、回肠、结肠的粘膜腺上皮细胞胞质内呈强阳性表达;胍基丁胺在大脑皮层、丘脑、海马、延髓的神经元胞质和神经轴突内呈强阳性表达;胍基丁胺在子宫、输卵管、前列腺的腺上皮细胞和睾丸的生精细胞胞质内呈强阳性表达;胍基丁胺在肝细胞、肾上腺皮髓质细胞胞质内呈阳性表达,在肾脏、脾脏呈弱阳性表达;胍基丁胺在肺、阴茎的微血管平滑肌细胞胞质内呈强阳性表达,但在心脏、骨骼肌、食道、主动脉的肌细胞内未见其表达。结论胍基丁胺在成年Wistar大鼠体内广泛分布,可能具有重要的生理作用。
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| 关 键 词： | 胍基丁胺 免疫组织化学 |
EXPRESSION AND DISTRIBUTION OF AGMATINE IN ADULT RATS |
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| Jiang Chunhua,Xiang Dekun,Huang Qingyuan,Gao Yuqi. EXPRESSION AND DISTRIBUTION OF AGMATINE IN ADULT RATS[J]. Chinese Journal of Histochemistry and Cytochemistry, 2009, 18(6): 696-700. DOI: 10.3870/zgzzhx.2009.06.017 |
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| Authors: | Jiang Chunhua Xiang Dekun Huang Qingyuan Gao Yuqi |
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| Affiliation: | Jiang Chunhua,Xiang Dekun,Huang Qingyuan,Gao Yuqi(1Department of Pathophysiology and Hgih Altitude Physiology,College of High Altitude Military Medicine,The Third Military Medical University,2Key Laboratory of High Altitude Medicine,Ministry of Education,3 Key Laboratory of High Altitude Physiology and High Altitude Disease,PLA,Chongqing 400038,China) |
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| Abstract: | Objective To observe the expression and distribution of agmatine in adult Wister rats.MethodsBy means of immunohistochemistry,self-made anti-agmatine polyclonal-antibodyies were applied to detect the expression of agmatine in adult Wirster rats.ResultsAgmatine was massively expressed in the cytoplasm of glandular epitheliums in stomach,duodenum,jejunum,ileum and colon,the cytoplasm or axon of neurons in cerebral cortex,thalamus,hippocampus and medulla oblongata,the cytoplasm of glandular epitheliums in uter... |
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| Keywords: | Agmatine Immunohistochemistry |
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