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Blood coagulation factor VIII: An overview |
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| Authors: | |
| Institution: | (1) Research and Development Division, Hindustan Antibiotics Ltd., 411 018 Pimpri, Pune, India |
| Abstract: | Factor VIII (FVIII) functions as a co-factor in the blood coagulation cascade for the proteolytic activation of factor X by factor IXa. Deficiency of FVIII causes hemophilia A, the most commonly inherited bleeding disorder. This review highlights current knowledge on selected aspects of FVIII in which both the scientist and the clinician should be interested. |
| Keywords: | Blood coagulation factor VIII hemophilia A replacement therapy |
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