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Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations
Authors:Suad Oded  Rozenberg Haim  Brosh Ran  Diskin-Posner Yael  Kessler Naama  Shimon Linda J W  Frolow Felix  Liran Atar  Rotter Varda  Shakked Zippora
Institution:1 Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100, Israel
2 Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel
3 Department of Chemical Research Support, Weizmann Institute of Science, Rehovot 76100, Israel
4 Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Ramat Aviv 69978, Israel
Abstract:
Keywords:wt  wild type  mutp53  mutant p53  PI  propidium iodide  qPCR  quantitative real-time PCR  PEG  polyethylene glycol
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