Reduced levels of adenosine deaminase in chick embryo fibroblasts transformed by Rous sarcoma virus. |
| |
| Authors: | P K Chiang G L Cantoni D A Ray J P Bader |
| |
| Affiliation: | Laboratory of General and Comparative Biochemistry National Institute of Mental Health Bethesda, Maryland 20014 USA;Laboratory of Tumor Virus Genetics National Cancer Institute National Institutes of Health Bethesda, Maryland 20014 USA |
| |
| Abstract: | Adenosine deaminase activities in chick embryo fibroblasts were substantially reduced after infection and transformation by Rous sarcoma virus. Concomitant with the reduction in adenosine deaminase activities, the incorporation of exogenous adenosine into RNA species of the virus transformed cells was moderately increased. The significance between reduction in adenosine deaminase activity and malignant transformation by Rous sarcoma virus remains to be eleucidated. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
