化学品生物合成专刊序言

以酶及微生物细胞催化剂结合工程学方法将廉价、废弃原料进行高效生物转化可实现化学品的可持续生产。近年来，合成生物学、系统生物学及酶工程等技术的快速发展大大推动了化学品的可持续生物制造，既实现了多种新型化学品的生物合成，又显著提高化学品的生物合成效率。为展示化学品生物合成的最新进展并促进绿色生物制造的发展，《生物工程学报》特组织出版化学品生物合成专刊，从酶催化与生物合成机制、微生物细胞合成、一碳生物炼制以及关键核心技术等方面，介绍化学品生物合成的最新前沿、挑战以及潜在解决方案。

Preface for special issue on chemical bioproduction

Engineering efficient enzymes or microbial cell factories should help to establish green bio-manufacturing process for chemical overproduction. The rapid advances and development in synthetic biology, systems biology and enzymatic engineering accerleate the establishing feasbile bioprocess for chemical biosynthesis, including expanding the chemical kingdom and improving the productivity. To consolidate the latest advances in chemical biosynthesis and promote green bio-manufaturing, we organized a special issue on chemical bioproduction that including review or original research papers about enzymatic biosynthesis, cell factory, one-carbon based biorefinery and feasible strategies. These papers comprehensively discussed the latest advaces, the challenges as well as the possible solutions in chemical biomanufacturing.