Abstract: | The interaction of mycoplasmas and mouse lymphocytes has been studied by the microbiological and electron-microscopic methods. The experiments have shown that A. laidlawii and M. arthritidis are adsorbed on lymphocytes and thymocytes of (C57BL6 X A/He)F1, BALB and C57BL mice after 15 minutes of their joint incubation at 37 degrees C, 1 hour later adsorption reaches its maximum intensity and after further prolongation of the time of incubation the number of adsorbed microbial cells remains unchanged. The first stage of the interaction of mycoplasmas with splenic and thymic lymphocytes (adsorption) is the same in (C57BL6 X X A/He)F1, BALB and C57BL mice, and differences in the persistence of mycoplasmas in mice of the above strains are probably due not to different capacity of the cells for adsorbing mycoplasmas, but to differences in the immune status of these animals. |