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Production of Soluble and Functional Anti-TNF-α Fab' Fragment in Cytoplasm of E. coli: Investigating the Effect of Process Conditions on Cellular Biomass and Protein Yield Using Response Surface Methodology |
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| Authors: | Talaei Andisheh Mazaheri Somayeh Bayat Elham Bakhshandeh Behnaz Sabzalinejad Masoumeh Damough Shadi Mahboudi Fereidoun Nematollahi Leila Talebkhan Yeganeh |
| Institution: | 1.Department of Biotechnology, College of Science, University of Tehran, Tehran, Iran ;2.Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran ; |
| Abstract: | The Protein Journal - With the increasing dominance of monoclonal antibodies (mAbs) in the biopharmaceutical industry and smaller antibody fragments bringing notable advantages over full-length... |
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| 本文献已被 SpringerLink 等数据库收录！ | |